Surface Modification of PVDF Membrane with a Caffeic Acid-Imprinted Polymer Layer
Combination of imprinting and membrane technology allowed to prepare molecularly imprinted membrane having great potential application in molecular separation and purification on the valuable herbal extraction. This technology offers the advantage of combining the mechanical integrity of the membrane support with the selective recognition properties of the imprinted polymer layer. The purpose of this work was to prepare a highly specific molecular imprinted membrane (MIM) towards extraction of caffeic acid by surface modification of microfiltration polyvinyldine floride (PVDF) with a thin layer of molecular imprinted polymer. The imprinted membranes were fabricated utilizing caffeic acid as the template, 4-Vinylpyridine (4-VP) as the functional monomer and ethylene glycol dimethacrylate (EGDMA) as the cross-linker via thermal polymerization process. Blank imprinted membranes were prepared with the same monomer and cross-linker composition but in the absence of the template. The imprinted membranes were characterized through the Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscope (SEM) to prove that the polymerization process successfully prepared on the surface of the PVDF membranes. The molecular imprinted membrane (MIM) showed the thicker fibrous membrane structure compare to the non-imprinted membrane (NIM). The binding performance indicated that the MIM obtained the highest caffeic acid adsorption of 0.22 mg/g at concentration of 12 mg/L. MIM also have higher selectivity towards caffeic acid compared to other structural analogues. The imprinted membrane prepared in this work could be applied as new separation devices in affinity filtration aimed to extract caffeic acid content in raw herbal materials.
Open Access authors retain the copyrights of their papers, and all open access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided that the original work is properly cited.
The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.
While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.